Showing posts with label physician. Show all posts
Showing posts with label physician. Show all posts

19 March 2020

Filippo Mazzei – physician

Liberal thinker was praised by John F Kennedy


Filippo Mazzei contributed to the wording of America's Declaration of Independence
Filippo Mazzei contributed to the wording
of America's Declaration of Independence
Globe-trotting doctor Filippo Mazzei, who was a close friend of the American president, Thomas Jefferson, died on this day in 1816 in Pisa in Tuscany.

During the American Revolutionary War, Mazzei had acted as an agent for Jefferson, purchasing arms for Virginia.

President John F Kennedy paid tribute to Mazzei’s contribution to the Declaration of Independence in his book, A Nation of Immigrants.

Mazzei was born in 1730 in Poggio a Caiano in Tuscany. He studied medicine in Florence and then practiced in both Italy and Turkey. He moved to London in 1755 and set himself up in business as an importer, while also working as an Italian teacher.

In London he met both Benjamin Franklin and Thomas Jefferson, who would become two of America's Founding Fathers, and came up with the idea of importing Tuscan products, such as wine and olive trees, to the New World.

In 1773 Mazzei boarded a ship from Livorno to Virginia, taking with him plants, seeds, silkworms and farmers from Lucca.

He visited Jefferson at his estate in Virginia and was given a large piece of land to start an experimental plantation.

Thomas Jefferson and Filippo Mazzei shared similar political values
Thomas Jefferson and Filippo Mazzei
shared similar political values
Mazzei and Jefferson started what was to become the first commercial vineyard in Virginia. They were both interested in politics and discovered they shared similar liberal values, becoming good friends.

After Mazzei returned to Italy in 1779 he became a secret agent for the state of Virginia, buying and shipping arms to them.

He also travelled through Europe promoting Republican ideals, writing a political history of the American Revolution, which he published in Paris in 1788.

While in the Polish Lithuanian commonwealth, Mazzei became attached as a Privy Councillor to the court of King Stanislaus II. The King then sent him to be Poland’s representative in Paris.  After Poland was partitioned between Russia and Prussia in 1795, Mazzei was given a pension by Russia.

While in France, Mazzei became active in the politics of the French Revolution under the Directorate, but when Napoleon overthrew that Government, Mazzei returned to Pisa, where he died in 1816. He was buried in the Pisa Suburbano cemetery.

It has been claimed that Jefferson had a falling out with George Washington over a letter he had sent to Mazzei in Italy that criticised Washington’s administration. The letter was eventually published overseas and in the US.

A plaque marks the house in Via Giordano Bruno in Pisa where Filippo Mazzei died on March 19, 1816
A plaque marks the house in Via Giordano Bruno in Pisa
where Filippo Mazzei died on March 19, 1816
But John F Kennedy acknowledges Mazzei’s contribution to the Declaration of Independence in his book: A Nation of Immigrants. He states: ‘The great doctrine ‘All men are created equal’ and incorporated into the declaration of Independence by Thomas Jefferson was paraphrased from the writing of Philip Mazzei, an Italian-born patriot and pamphleteer, who was a close friend of Jefferson.’

Kennedy said in his book that scholars try to discredit Mazzei as the creator of this statement but he insists that it was written in Italian in Mazzei’s own hand several years before the Declaration was written.

Kennedy writes: ‘No one man can take complete credit for the ideals of American democracy.’

In 1980 a 40-cent US airmail stamp was issued to commemorate the 250th anniversary of Mazzei’s birth. The World War II Liberty Ship SS Filippo Mazzei was also named in his honour.

Mazzei lived his final years in a house in Via Giordano Bruno in Pisa, which is identified to visitors by a plaque on the wall. He was said to have been a regular visitor to the Caffè dell’Ussero, a coffee house frequented by intellectuals that occupies the ground floor of the Palazzo Agostini, a striking four-storey Gothic building by the river on Lungarno Antonio Pacinotti.

The Villa Medici at Poggio a Caiano, where visitors can view apartments used by the Medici family
The Villa Medici at Poggio a Caiano, where visitors can
view apartments used by the Medici family
Travel tip:

Poggio a Caiano, where Filippo Mazzei was born, is a town and comune in the province of Prato in Tuscany. It lies nine kilometres south of the provincial capital of Prato. One of the most famous sights in the area is the Villa Medici, designed by Giuliano da Sangallo in around 1480. Today it is a public building housing a museum and the historic apartments where members of the Medici family used to stay.

Poggio a Caiano hotels with Booking.com

Pisa's Torre Pendente - the leaning tower - is a monument recognised all over the world
Pisa's Torre Pendente - the leaning tower -
is a monument recognised all over the world
Travel tip:

Pisa, where Filippo Mazzei died and was buried, is famous for its leaning tower, Torre Pendente, which is one of the four buildings that make up the cathedral complex in the Field of Miracles (Campo dei Miracoli). The Duomo was the first to be constructed and then the Baptistery was added. While work on the tower was being carried out, a cemetery (Campo Santo) was added. During the summer the tower is open to visitors from 08.30 to 22.00. Tickets to climb the tower are limited and booking in advance is recommended if you want to avoid queuing. For more details, visit www.towerofpisa.org/tickets.

4 October 2019

Bernardino Ramazzini - physician

Pioneer in knowledge of occupational diseases, cancer and malaria


Ramazzini worked in medicine for more than half a century
Ramazzini worked in medicine
for more than half a century
The physician Bernardino Ramazzini, often described as the “father of occupational medicine” and responsible also for pioneering work in the study of cancer and the treatment of malaria, was born in Carpi in Emilia-Romagna on this day in 1633.

Ramazzini’s tour de force, which he completed at the age of 67, was his book De Morbis Artificum Diatriba - Discourse of the Diseases of Workers - which came to be regarded as a seminal work in his field, the lessons from which still influence practice today in the prevention and treatment of occupational diseases.

A student at the University of Parma, Ramazzini was appointed chair of theory of medicine at the University of Modena in 1682 and professor of medicine at the University of Padua from 1700 until his death in 1714.

It was while he was in Parma that he began to take an interest in diseases suffered by workers.

When he became a departmental head at Modena, he began to study the health problems of workers in a more systematic way.  He would visit their workplaces, observe the activities they undertook in their work and discuss their health problems with them.

Ramazzini could see that some diseases were attributable to the materials they worked with, including chemicals that would now be classified as hazardous, or the dangers posed by equipment.

The first page of the 1713 edition of Ramazzini's work on the study of occupational diseases
The first page of the 1713 edition of Ramazzini's work
on the study of occupational diseases
Where he was ahead of his time was in observation that other ailments common among workers appeared to be related to how they carried out their work, and whether it involved prolonged, violent, and irregular movements.

Ramazzini saw a relationship between certain disorders and the repetition of particular motions, or the lifting of heavy objects, but also noted that certain diseases appeared to be prevalent in workers whose environment restricted the amount of movement, such as sitting for long periods.

This research formed the basis of many of his lectures and he recommended to doctors treating sick patients that their diagnostic questions should include asking about the patient’s place of work.

Ultimately Ramazzini was able to group his findings in to four areas: occupations that require workers to handle minerals and metals or other raw materials extracted from the earth; workers exposed to air-borne toxins; workers exposed to fluids such as water, milk and alcoholic beverages; and workers whose jobs involved unnatural postures or positions held for long periods.

Ramazzini made important observations about cancer and malaria
Ramazzini made important observations
about cancer and malaria
He also emphasised, again displaying a level of understanding that was perhaps centuries ahead of his time, that other factors could be linked to the degree to which an individual’s working environment impacted his or her health, such as social status and lifestyle.

Ramazzini took 10 years to bring together all his observations in De Morbis Artificum Diatriba, which carried the authority of more than 40 years in medical practice.  He urged physicians to promote the thinking that prevention was as important in cure.

Away from occupational health, Ramazzini was one of the first to point science towards the role that hormones might play in the development of some cancers.  This was based on his observations that there was a virtual absence of cervical cancer among nuns, but a high incidence of breast cancer, which he postulated as possibly due to their abstinence from sexual activity.

He was also one of the first to support the use of quinine - found in the bark of the cinchona tree - as a treatment for malaria.

Ramazzini died in Padua in November, 1714.

The Castello del Pio on Piazza Martiri in Carpi, one of the largest public squares in Italy
The Castello del Pio on Piazza Martiri in Carpi, one of the
largest public squares in Italy
Travel tip:

Carpi, where Ramazzini was born, is situated about 18km (11 miles) north of Modena in the Padana plain. It became a wealthy town during the era of industrial development in Italy as a centre for textiles and mechanical engineering. Its historic centre, which features a town hall housed in a former castle, is based around the Renaissance square, the Piazza Martiri, the third largest square in Italy. Italy’s national marathon has finished in Carpi in 1988 in honour of another of the town’s famous sons, the marathon runner Dorando Pietri.

The Duomo and Palazzo Communale in Piazza Grande in the heart of Modena
The Duomo and Palazzo Communale in Piazza Grande
in the heart of Modena
Travel tip:

Modena, where Ramazzini spent part of his academic life, is a city on the south side of the Po Valley.  It is known for its car industry, as Ferrari, De Tomaso, Lamborghini, Pagani and Maserati have all been located there. The city is also well known for producing balsamic vinegar. Operatic tenor Luciano Pavarotti and soprano Mirella Freni were both born in Modena.  One of the main sights in Modena is the huge, baroque Ducal Palace, which was begun by Francesco I on the site of a former castle in 1635. His architect, Luigi Bartolomeo Avanzini, created a home for him that few European princes could match at the time. The palace is now home to the Italian national military academy.

Also on this day:

1657: The birth of Neapolitan painter Francesco Solimena

1720: The birth of print maker and architect Giovanni Battista Piranesi

The Feast of Saint Francis of Assisi


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