Showing posts with label Health. Show all posts
Showing posts with label Health. Show all posts

28 November 2023

Umberto Veronesi - oncologist

Pioneered new techniques for treating breast cancer

Umberto Veronesi made an important contribution to breast cancer treatment
Umberto Veronesi made an important
contribution to breast cancer treatment 
Umberto Veronesi, an oncologist whose work in finding new methods to treat breast cancer spared many women faced with a full mastectomy, was born on this day in 1925 in Milan.

Along with many other contributions to the knowledge of breast cancer and breast cancer prevention over a 50-year career, Veronese was a pioneer of breast-conserving surgery in early breast cancer as an alternative to a radical mastectomy. 

He developed the technique of quadrantectomy, which limits surgical resection to the affected quarter of the breast. 

This more limited resection became standard practice for the treatment of breast cancer detected early after Veronesi led the first prospective randomised trial of breast-conserving surgery, which compared outcomes from radical mastectomy against his quadrantectomy over a 20-year period.

Veronesi supported and promoted research aimed at improving conservative surgical techniques in general and conducting studies on tamoxifen and retinoids which helped verify their effectiveness in preventing the formation of cancer in the first place. 

The founder and president of the Umberto Veronesi Foundation, he founded and held the role of scientific director and scientific director emeritus of the European Institute of Oncology, was scientific director of the National Cancer Institute of Milan and held the position of Minister of Health from April 2000 to June 2001 in the second government of prime minister Giuliano Amati.

Veronesi grew up in Casoretto, which was then an agricultural suburb of Milan, where his father was a tenant farmer.  He was one of six children. The family home was relatively remote, the only source of heat in the winter a fireplace in the kitchen. Going to school necessitated a 5km (three miles) walk to school and back, but his parents were determined that their five sons and a daughter would enjoy a good education.

Veronesi pictured at a book signing in 2013, still working at the age of 87
Veronesi pictured at a book signing in 2013, still
working at the age of 87
Veronesi’s father died when he was still a child but the memory of beatings handed out by Fascist squadristi meant that his father’s left-wing politics had a more profound effect on him than his mother’s devout Catholicism. He declared himself to be an agnostic at the age of 14.

He began to focus on cancer soon after graduating in medicine and surgery at the University of Milan in 1951 and specialising in surgery at the University of Pavia. He travelled to England and France to broaden his knowledge and joined the National Cancer Institute, of which he would become director-general in 1975, as a volunteer.

In the course of what would be a brilliant career, his far-sighted ideas were not well received initially and he had to fight to convince others.  Yet in time his scientific projects opened new boundaries in cancer treatment.  His belief in joining forces with patients, communicating with them clearly about their treatment and enlisting their help in campaigns to raise funds helped change attitudes towards the disease.

Veronesi too was instrumental in removing regulatory barriers in the management of terminal cancer patients, making opioid painkillers available to those whose cancer could not be cured.

Veronesi (right) with then president Giorgio Napolitano in 2011
Veronesi (right) with then president
Giorgio Napolitano in 2011
Away from the main focus of his life, Veronesi became politically active when the left-wing politician Bettino Craxi invited him to become a member of the national assembly of the Italian Socialist Party (PSI).  In April 2000 he was Minister of Health in the second Amato government, using his platform to campaign for an anti-smoking law.  He was later elected to the Senate as a member of the Democratic Party.

President of the Italian Nuclear Safety Agency from 2010-11, he resigned from that position in protest at the Berlusconi government for failing to provide the agency with even the minimum structures to carry out its activities.

He was a strong advocate of animal rights, believed in voluntary euthanasia and, controversially, supported the genetic modification of food because of its possibilities for helping parts of the world prone to crop failures and famine, and for removing naturally occurring carcinogens. 

His outspoken opposition to doctors’ strikes in the 1980s, however, caused him to fall foul of the Red Brigades, whose death threats left him looking over his shoulder in public for several years.

Veronesi died at home in November 2016 not long before what would have been his 91st birthday. After a secular funeral at Palazzo Marino, Milan’s city hall, where his son, Alberto, a conductor, led two musical pieces by Beethoven and Puccini, his body was cremated. 

Via Casoretto, looking towards the church of Santa Maria Bianca della Misericordia
Via Casoretto, looking towards the church of
Santa Maria Bianca della Misericordia
Travel tip:

The Casoretto of today is a neighbourhood in the northeastern suburbs of Milan, forming part of an area locally known as NoLo, an acronym for North of Loreto. The area is multicultural with a vibrant nightlife, art galleries and restaurants. Casoretto is notable for colourful houses and an unusually high number of cycle repair shops, reflecting local beliefs in eco-friendly travel.  The neighbourhood fans out from the central Via Casoretto and the church of Santa Maria Bianca della Misericordia, which is sometimes known as the Abbey of Casoretto. Until the start of the 20th century and industrialisation, the area was characterised by farmhouses and cultivated fields, with no significant residential areas apart from a few farmhouses and other buildings around the Abbey.


Palazzo Marino, with the entrace to the Galleria Vittorio Emanuele II to the right of the picture
Palazzo Marino, with the entrace to the Galleria
Vittorio Emanuele II to the right of the picture
Travel tip:

Palazzo Marino, where Veronesi’s secular funeral was held, is a 16th-century palace located in Piazza della Scala, in the centre of Milan. Standing opposite the world-famous opera house, Teatro alla Scala, and next to the northern entrance to the Galleria Vittorio Emanuele II, it has been Milan’s city hall since 1861. Designed by architect Galeazzo Alessi, it was built between 1557 and 1563 for Tommaso Marino, a wealthy Genovese banker and merchant.  After Marino died, leaving his family bankrupt, the palace became the property of the state before being sold to another banker, Carlo Omodei, who did not live there himself but rented it out to other notable Milanese, before reverting to state ownership in 1781. After being established as the seat of Milan’s municipal government in 1861, the palace was given a new facade to coincide with the creation of Piazza della Scala, undergoing a second major restoration after it was badly damaged by bombing in World War Two. 

Also on this day:

1873: The death of astronomer Caterina Scarpellini

1907: The birth of novelist Alberto Moravia

1913: The birth of composer Mario Nascembene

1941: The birth of actress Laura Antonelli

1955: The birth of footballer Alessandro Altobelli

1977: The birth of World Cup hero Fabio Grosso


Home


21 April 2022

Gino Strada - surgeon and charity founder

‘Maestro of humanity’ built hospitals for war victims

Gino Strada's charity has helped more than 11 million people worldwide
Gino Strada's charity has helped more
than 11 million people worldwide
The surgeon and founder of the medical and humanitarian charity Emergency, Gino Strada, was born on this day in 1948 in Sesto San Giovanni, a town that is now effectively a suburb of Milan.

Emergency has provided free healthcare to more than 11 million people in 19 different countries, including locations severely affected by conflict such as Afghanistan, Iraq, and Yemen.  It also operates in Eritrea, Sierra Leone, Uganda, Sudan, Cambodia, Serbia, Nicaragua and Sri Lanka.

The hospitals set up by the organisation - some designed with the help of Strada’s friend, the world-renowned architect Renzo Piano - are built to the highest standards, with the aim of providing world-class treatments and after-care. Strada, who was said himself to have performed more than 30,000 operations on direct or indirect victims of conflict, insisted that the hospitals in which his European volunteers worked had to be places where “you would be happy to have one of your family members treated”,

When Strada died in 2021, among the many tributes paid to him was one by the then president of the European parliament, David Sassoli, who described him as the ‘maestro of humanity’.

The son of a steelworker, Strada attended the Liceo Classico Giosuè Carducci, a high school specialising in science near Milano Centrale railway station. He then studied medicine and trauma surgery at the University of Milan, where he graduated in 1978, before training as a heart-lung transplant surgeon in the United States and South Africa.

The Emergency organisation's logo
The Emergency organisation's logo has become
a familiar sight in 19 countries since 1994
He returned to Italy to work at a hospital in Rho, to the northwest of Milan. A committed peace activist, he soon focussed his attention on trauma surgery and in particular the treatment of war victims.

In 1988, he began to work as a surgeon with the International Committee of the Red Cross in various conflict zones, including Pakistan, Ethiopia, Peru, Afghanistan, Thailand, Djibouti, Somalia and Bosnia.

He founded Emergency in 1994, along with his then-wife, Teresa, and with the support of colleagues. They provided their first medical services in Rwanda in the wake of the genocide there, when an 800,000 people were killed by Hutu extremists. 

Funded mainly through private donations, Emergency has cared for the civilian victims of land mines, improvised explosive devices, bombings, suicide attacks and of the diseases that flourish in communities without access to proper sanitation and medical services as a result of conflict.

Strada worked in Italy at the height of the Covid-19 pandemic
Strada worked in Italy at the
height of the Covid-19 pandemic
The organisation also cared for Ebola patients in Sierra Leone and, in Khartoum, Sudan, children whose hearts were damaged by rheumatic fever.

Emergency also set up a hospital in Afghanistan's Panjshir Valley, followed by others in Kabul and Lashkar Gah. Rigorously neutral in all conflicts, Strada spent several periods living in Afghanistan, where he once negotiated with Taliban leader Mohammed Omar and the leaders of rival Northern Alliance to ensure the safety of Emergency patients on both sides of the conflict. 

Strada preferred Emergency to remain non-political, but he found it impossible at times to be neutral. He opposed Italy’s involvement in Kosovo in 1999 and was an outspoken critic of the US-led invasion of Iraq in 2003. When Italy banned the manufacture, sale and export of anti-personnel landmines in 1997, it was in part due to a lobbying campaign by Emergency.

After decades taking on medical challenges in remote corners of the world, Strada found that the coronavirus pandemic created a demand for Emergency’s services in his native Italy, the first western country to be ravaged by the disease in 2020. The organisation provided medical care in the hardest-hit cities, as well as helping with delivering medicine and provisions for vulnerable people during lockdowns and handing out free food other essentials for Italians impacted by the economic consequences of the pandemic.

Widowed in 2009 when his wife, Teresa, died, Strada remarried in June 2021 to Simonetta Gola, Emergency's communications manager, but less than two months after the wedding he fell victim to a heart attack while on holiday in France and sadly passed away at the age of 73.

Although he had a history of heart trouble, his death came as a shock to many as he had shown no sign of slowing down.  His daughter by his first marriage, Cecilia, is a former president of Emergency. The current president is Rossella Miccio.

The suburb of Sesto San Giovanni in Milan
The suburb of Sesto San Giovanni in Milan has
transitioned from industrial to business centre
Travel tip:

Sesto San Giovanni, where Gino Strada was born, is the northernmost point on the Milan M1 metro line. In the 1920s it had a population of just over 15,000 but began to expand as an industrial centre, becoming the base for several large companies in the steel and motor industries but also the Campari drinks company.  The years after the Second World War saw a huge influx of migrants from other parts of Italy, attracted by the job possibilities. Today, the area is a busy suburb with more than 85,000 inhabitants. The current employers are more in the service sector, such as the telecommunications company, WIND.




The facade of Milano Centrale railway station
The facade of Milano Centrale railway station
was designed by Ulisse Stacchini in 1931
Travel tip:

Milano Centrale station, close to where Gino Strada went to high school, is one of Italy’s busiest rail hubs. It has 24 platforms and handles about 320,000 passengers per day, using approximately 500 trains. The station is an important stop on the north-south route between Bologna and Salerno and also has trains running daily to international destinations including Bern, Lugano, Geneva, Zürich, Paris, Vienna, Barcelona and Munich. It was designed by the architect Ulisse Stacchini, a champion of Liberty style Art Nouveau designs, who also designed the stadium that evolved into the city's iconic Stadio Giuseppe Meazza, joint home of Milan's two major football clubs, Internazionale and AC Milan.

Also on this day:

753 BC: The founding of the city of Rome

1574: The death of Tuscan leader Cosimo I de' Medici

1922: The death of castrato singer Alessandro Moreschi

1930: The birth of actress Silvana Mangano


Home







26 December 2018

Piergiorgio Welby - euthanasia campaigner

Muscular dystrophy sufferer who fought for right to die


Piergiorgio Welby was kept alive by an artificial breathing mechanism for the last nine years of his life
Piergiorgio Welby was kept alive by an artificial breathing
mechanism for the last nine years of his life
The poet, painter and muscular dystrophy sufferer Piergiorgio Welby, whose wish to be given help to die after nine years being kept alive artificially sparked a huge legal, political and religious debate, was born on this day in 1945 in Rome.

Welby, the son of an AS Roma footballer with Scottish ancestry, developed MS when he was 17 years old.

Throughout the 1960s and 70s his lifestyle helped keep the disease under control. He lived as an artist and writer, following the hippie movement but also hunting and fishing. His use of recreational drugs dulled the symptoms of the disease and he was able to travel extensively in Europe.

During this period he met his future wife, Wilhelmine - later known as Mina - who was from Bolzano province in Trentino-Alto Adige but encountered Welby in Rome.

Welby decided in the 1980s to wean himself off drugs by embarking on methadone therapy, but the disease then progressed rapidly and he was soon paralysed from the waist down.  In 1997, he suffered severe respiratory problems and from that point onwards was dependent on a breathing tube.  As well as mechanical ventilation, he depended on artificial feeding.

It was at this point he began to write and talk - he had a voice synthesizer - about euthanasia and joined the Italian Radical Party, the political organisation closest to his views.  In time, though, he lost even the ability to control a computer mouse.

Euthanasia was and remains illegal in Italy, largely due to the strict opposition of the Catholic Church, and though a patient has a right to refuse treatment, a doctor is still required to make every attempt to keep the patient alive.

Up to 1,000 people attended Piergiorgio Welby's secular funeral in Piazza Don Bosco in the Tuscolano district
Up to 1,000 people attended Piergiorgio Welby's secular
funeral in Piazza Don Bosco in the Tuscolano district
In September 2006, Welby sparked the political debate that was eventually to bring matters to a head by dictating an open letter to the Italian president, Giorgio Napolitano, which was shown on national television and reported extensively in the national press.

“I love life, Mr. President,” Welby wrote. “Life is the woman who loves you, the wind through your hair, the sun on your face, an evening stroll with a friend.

“Life is also a woman who leaves you, a rainy day, a friend who deceives you. I am neither melancholic nor manic-depressive. I find the idea of dying horrible. But what is left to me is no longer a life.”

Napolitano expressed his sympathy with Welby’s plight and invited politicians to debate the issue.

There were heated exchanges in the Italian parliament and political TV shows, around the political, ethical, religious and medical aspects of the case.

The Radical Party founder Marco Pannella said he was willing to turn off Welby’s life-support equipment himself as an "act of civil disobedience".

The outspoken Radical Party founder Marco Pannella was a supporter of Welby's cause
The outspoken Radical Party founder Marco
Pannella was a supporter of Welby's cause
Most Catholic politicians stood by the official position of the Catholic Church. Health Minister Livia Turco said that a parliamentary debate should focus more on improving palliative care rather than on euthanasia.

Welby’s right to refuse treatment under the Italian constitution and the code of conduct of Italian doctors was confirmed by a court ruling, but the doctor’s obligation to try to revive a patient in distress remained in place.

Eventually, an anaesthetist, Mario Riccio contacted the Radical Party and said he was prepared to switch off Welby’s life support, seeing no legal impediments. On December 20 he visited him in hospital in the presence of his wife Mina and daughter Carla and some supporters, including Marco Pannella, administered sedation and disconnected all the devices keeping him alive. He was pronounced dead 40 minutes later, at 11.40pm.

Welby’s death was announced the following morning by Pannella and a press conference followed later.

Luca Volonté, a Christian Democrat, called for Riccio to be arrested and charged with murder and had strong support in public opinion polls, but the the following March both the Ethical Committee of the Italian Medical Association and investigating magistrates declared Dr Riccio’s conduct to be lawful.

Controversially, the Catholic Church refused to allow Welby a religious funeral, declaring that his repeated public affirmations of his desire to end his own life were against Catholic doctrine.

Nonetheless, up to 1,000 people attended a secular funeral on December 24, 2006 in Piazza Don Bosco in the Tuscolano quarter of Rome, in front of the church that the family had chosen for the religious ceremony.

The town of San Candido is close to the Austrian border
The town of San Candido is close to the Austrian border
Travel tip:

Mina Welby’s home town of San Candido, also known as Innichen, is in northern Italy, close to the border with Austria. It’s part of the Tre Cime Natural Park, in the Dolomites. Among the main sights in the historical centre is the Romanesque-style Innichen Abbey, with a frescoed dome, and the DoloMythos Museum, exploring local natural history. The area has a strong military history, being home to the Druso and Cantatore barracks, the latter housing the 6th Alpine Regiment of the Italian Army.  A short distance outside San Candido is a sanctuary where the bodies of more than 200 soldiers killed in the First World War were buried.


The Aqua Marcia aqueduct passes through the Tuscolano quarter of Rome, along with several others
The Aqua Marcia aqueduct passes through the Tuscolano
quarter of Rome, along with several others
Travel tip:

Tuscolano is the 8th quartiere of Rome and is named after the Via Tuscolana that runs through it. It is one of the biggest districts of Rome, starting just outside the old city walls, near the Basilica of San Giovanni in Laterano, and stretches all the way to the Via del Quadraro in the east. Its northern border is the Via Casilina and its southern border is the Via Appia Nuova. The Via del Mandrione is lined by huge walls that supported five of the ancient Roman aqueducts - the Aqua Marcia, Aqua Tepula, Aqua Iulia, Aqua Claudia and the Anio Novus.


More reading:

Giorgio Napolitano - Italy's 11th President

Marco Pannella, the campaigner who helped shape modern Italy

Augusto Odone, inventor of 'Lorenzo's Oil'

Also on this day:

The Feast of Santo Stefano

1912: The birth of artist Renato Gattuso

1956: The birth of writer and journalist Beppe Severgnini


Home

11 January 2018

The Giannini sextuplets

The multiple birth that made history


Rosanna Gemelli and her babies featured on  the cover of Gente magazine each year
Rosanna Giannini and her babies featured on
 the cover of Gente magazine each year 
History was made on this day in 1980 when a schoolteacher from the Casentino valley in Tuscany gave birth to sextuplets in a hospital in Florence.

The babies – four boys and two girls – delivered between 4.17am and 4.22am at the Careggi Hospital, on the northern outskirts of the Tuscan capital, grew to become the first sextuplets in Europe to survive beyond infancy and only the second set in the world.

Their arrival turned the Gianninis - mum Rosanna and dad Franco - into instant celebrities and their house in Soci, a village in the municipality of Bibbiena, 60km (37 miles) east of Florence, was besieged by the world’s media, seeking pictures and interviews.

In Italy, the event was celebrated with particular enthusiasm, heralded as the good news the nation craved after a particularly difficult year marked by a series of catastrophes, including the Ustica plane crash, the bombing of Bologna railway station and the Irpinia earthquake.

The family eventually signed an exclusive deal with the best-selling Italian magazine Gente for access rights.  Photographs of the children appeared around the time of their birthday for a number of years and features were written by the magazine’s leading journalist, Achille Mezzadri, who would later ghostwrite Rosanna’s autobiography, Vivere con sei gemelli – Living with sextuplets.

The couple – Rosanna was 29 and Franco 30 – faced uncharted territory in raising six babies simultaneously and faced enormous bills, too, first needing to find a house that would accommodate them all.

The sextuplets made the cover of Gente when they began to attend school
The sextuplets made the cover of Gente
when they began to attend school
They received help from the Tuscan regional government, while Rosanna’s revelation that she had to wash at least five loads of clothes every day prompted a major detergent company to propose a television advertising campaign for their products featuring the Giannini family.

The multiple pregnancy came about after Rosanna, desperate to start a family with Franco after being married in 1976, had been given hormone treatment after fearing she was entering an unnaturally early menopause.

She became pregnant in April 1979 but after feeling unwell during a particularly hot summer that year she was admitted to hospital for tests.  There she underwent an ultrasound scan and was astonished when the nurse carrying out the scan told her she was expecting twins, then spotted the third, fourth, fifth and sixth babies.

Her gynaecologist told her to keep her news a secret to avoid media attention ahead of the event but once the babies arrived there was no keeping it quiet.  By an amazing coincidence, the only other surviving sextuplets in the world at that time had been born in South Africa on January 11, 1974.

The six Giannini children – Letizia, Linda, Fabrizio, Francesco, Giorgio and Roberto – all weighed between 2lb 9oz (1.16kg) and 3lb 12oz (1.7kg) and thrived through childhood and adolescence, although Francesco came through a difficult time when he developed a serious kidney problem as a 19-year-old.

He slipped into a coma for a while and Rosanna credits the intervention of Don Alvaro, the parish priest of nearby Arezzo, who visited him in hospital and performed a blessing with the relics of Padre Pio, the much-venerated saint, for bringing about his recovery.

Rosanna pictured in 2015, aged 64, when her  famous sextuplets turned 35
Rosanna pictured in 2015, aged 64, when her
famous sextuplets turned 35
Media interest in the family naturally tailed off after a number of years but in 2015, on the occasion of the children’s 35th birthday, Rosanna gave an interview to the Italian newspaper La Stampa in which she lamented the fact that, despite four of the six obtaining degrees and the other two passing their high school exams, only Giorgio, a business economics graduate, had a permanent job, as an auditor for a company in Florence.

Of the others, Linda and Letizia, both graduates, were teaching but only on temporary contracts, Roberto had a job in a textile factory and Fabrizio, the other graduate, was working in a shopping mall with no job security.  Francesco had recently been laid off from his office job.

“In a way my children are emblematic of today’s Italy,” she said. “Four have degrees, the other two have high school certificates, and yet four do not have permanent or stable jobs.”

She and Franco had, though, become grandparents for the first time thanks to the arrival in 2014 of Letizia’s son, Tommaso.

The hilltop town of Bibbiena
The hilltop town of Bibbiena
Travel tip:

Bibbiena is an ancient town situated on a hill overlooking the Archiano river with a well-preserved medieval centre not well known to tourists but which contains a number of attractive palaces and churches, including the 14th century Chiesa di San Lorenzo and the 12th century Chiesa di Santi Ippolito e Donato. The town is surrounded by typical Tuscan countryside of rolling hills dotted with characteristic larch, beech and fir trees.  The town has a strong tradition of producing pecorino cheese.

Arezzo's sloping Piazza Grande
Arezzo's sloping Piazza Grande
Travel tip:

The city of Arezzo is well worth including in any Tuscan itinerary. Its central square, the sloping Piazza Grande, is as beautiful as any in Italy, while the city’s Duomo has painted vaulted ceilings and a 15th-century fresco of Mary Magdalene by Piero della Francesca. The Basilica di San Francesco has a chapel decorated with more Piero frescoes and inside the Basilica di San Domenico can be found a 13th-century Crucifix painted by Cimabue.  Piazza Grande hosts a large antiques fair every month and an annual medieval festival entitled the Saracen Joust, which features “knights” on horseback representing different areas of the city.