Hieronymus Fabricius - anatomist and surgeon

Research pioneer known as “Father of Embryology”

Girolamo Fabrizio spent much of his academic
life at the University of Padua

The pioneering anatomist and physiologist known in academic history as Hieronymus Fabricius, whose Italian name was Girolamo Fabrizio, was born on this day in 1537 in Acquapendente, in Lazio.

Fabrizio, who designed the first permanent theatre for public anatomical dissections, advanced the knowledge of the make-up of the human body in many areas, including the digestive system, the eyes and ears, and the veins.

But his most significant discoveries were in embryology.  He investigated the foetal development of many animals and humans and produced the first detailed description of the placenta. For this he became known as the "Father of Embryology".

Fabrizio spent most of his life at the University of Padua, where he was a student under the guidance of Gabriele Falloppio, who discovered the tube connecting the ovaries with the uterus that became known as the Fallopian tube.

He succeeded Falloppio as chair of surgery and anatomy, holding the post from 1562 to 1613 and building a reputation that attracted students from all of Europe.

Among his pupils were the English anatomist William Harvey, as well as Giulio Casseri and Adriaan van den Spiegel, both of whom went on to become significant anatomists in Italy. Indeed, both also occupied the chair of surgery and anatomy at the University of Padua.

The Teatro Anatomico at the University of Padua was
designed by Girolamo Fabrizio

Fabrizio’s dissections of animals enabled him to make discoveries about the formation of the fetus, the structure of the esophagus, stomach and intestines, and the workings of the eye, the ear, and the larynx. He was the first to note that the pupil of the eye changes in size.

He was the first to identify the membranous folds that he called "valves" in the interior of veins, which are now understood to prevent retrograde flow of blood within them.

Fabrizio also described the cerebral fissure separating the temporal lobe from the frontal lobe of the brain, although it is only recently that he has been credited with the discovery.

The statue of Girolamo Fabrizio in
his home town of Acquapendente

He was a practising surgeon as well as an anatomist. Extraordinarily, the technique he invented to perform a tracheotomy is very similar to the procedure used in the operation today.

Fabrizio never actually performed such an operation himself, but in his writing he described using a vertical incision and a tracheostomy tube, a short, straight cannula to which he added wings to prevent the tube from disappearing into the trachea.

The technique may have been used for the first time by the surgeon Marco Aurelio Severino during a diptheria epidemic in Naples in 1610.

Fabrizio died in Padua in 1619 at the age of 82. There is a monument to him in his home town of Acquapendente.

The castle at Torre Alfina, near Acquapendente

Travel tip:

Acquapendente is a medieval town in northern Lazio, about 140km (87 miles) north of Rome, just under 30km (18 miles) west of Orvieto. It takes its name - literally translated as ‘hanging water’ - from the small waterfalls that flow into the Paglia river. Among the main sights is the Duomo di Acquapendente, which developed from a former Benedictine monastery, developed in the 12th century. A short distance from Acquapendente is he castle of Torre Alfina, the central tower of which was built by the Lombard king Desiderius.

Palazzo Bo, the historic home of the University of Padua

Travel tip:

The founding of the University of Padua is officially recorded to have taken place in 1222 but this was actually the first time it was mentioned in an historical document, which means it is certainly older. It was formed when a large group of students and professors left the University of Bologna in search of more academic freedom. The first subjects to be taught were law and theology.

Also on this day:

1470: The birth of the poet Pietro Bembo, lover of Lucrezia Borgia

1943: The birth of the veteran singer Al Bano

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Vittorio Orlando - politician

Prime minister humiliated at First World War peace talks

Vittorio Orlando's reputation lay in
tatters following Paris peace talks

Vittorio Emanuele Orlando, the Italian prime minister best known for being humiliated by his supposed allies at the Paris peace talks following the First World War, was born on this day in 1860 in Palermo.

Elected to the Chamber of Deputies for the first time in 1897, Orlando had held a number of positions in government and became prime minister in 1917 following Italy’s disastrous defeat to the Austro-Hungarian army at Caporetto, which saw 40,000 Italian soldiers killed or wounded and 265,000 captured. The government of Orlando’s predecessor, Paolo Boselli, collapsed as a result.

Orlando, who had been a supporter of Italy’s entry into the war on the side of the Allies, rebuilt shattered Italian morale and the military victory at Vittorio Veneto, which ended the war on the Italian front and contributed to the collapse of the Austro-Hungarian empire, saw him hailed as Italy’s ‘premier of victory’.

However, his reputation was left in tatters when he and Sidney Sonnino, his half-Welsh foreign secretary, when to Paris to participate in peace talks but left humiliated after the territorial gains they were promised in return for entering the war on the side of Britain, France and the United States were not delivered.

Orlando’s ability to negotiate was not helped by his complete lack of English, while his bargaining position was undermined also by disagreements with Sonnino over what they wanted. As a result, Orlando was no match for US president Woodrow Wilson, British premier David Lloyd George and French prime minister Georges Clemenceau.

Orlando, second left, with Lloyd George, Clemenceau,
and Woodrow Wilson at the Paris peace talks

He failed to secure either of Italy’s main objectives at the peace talks, namely control of the Dalmatian peninsula and the annexation of the coastal city of Rijeka, known in Italian as Fiume, suffered a nervous collapse, for which he was mocked by Clemenceau in particular, and stormed out of the talks before their conclusion.

Orlando resigned as prime minister just days before the Treaty of Versailles to which he was supposed to have been a signatory.  Years later he spoke of his pride at having nothing to do with what was finally agreed but at the time he was seen as a failure.

The damage to national morale and pride was considerable.  Some historians believe Orlando’s humiliation was a key factor in Mussolini being able to harness so much public support and sweep to power.

Orlando’s backing for Mussolini - at the start of the Fascist regime, at least - enabled him to cling to his political career and in 1919 he was elected president of the Chamber of Deputies.  But he could not countenance the murder by the Fascists of the socialist politician Giacomo Matteotti in 1924 and quit politics in 1925.

He returned in 1944 after the fall of Mussolini and became speaker of the Chamber of Deputies. But he failed in his bid to be elected president of the Italian Republic in 1948, defeated in the vote by Luigi Einaudi.  He died four years later.

Sidney Sonnino disagreed with
Orlando's approach to the talks

The son of a Sicilian gentleman landowner, Orlando was a controversial figure even before the debacle of Paris.  Highly intelligent - he wrote extensively on legal and judicial issues - he was dogged throughout his career by accusations that had connections with the Sicilian Mafia.

His association with the mobster Frank Coppola, who was deported back to Sicily in 1948 after a criminal career in the United States, did not help, nor did a speech he made in the Italian senate in 1925 in response to rumours doing the rounds, in which he teased his audience by speaking about the Sicilian origins of the word mafia to mean a person of loyalty, honour, compassion and generosity of spirit and declaring himself “a proud mafioso”.

The Mafia pentito - state witness - Tommaso Buscetta once claimed in court that Orlando genuinely was a member of the Sicilian Mafia, although he was never investigated.

Looking across Partinico towards the Gulf of Castellammare

Travel tip:

Partinico, the town which Orlando represented when he was elected to the Italian parliament in 1897, is situated about 37km (23 miles) west of Palermo, on the way to Castellammare del Golfo. Home to almost 32,000 people today, it has long held political significance and was a stopover for Giuseppe Garibaldi during his march on Palermo.

The Duomo of Serravalle at Vittorio Veneto

Travel tip:

Vittorio Veneto is a town of some 28,000 people in the Province of Treviso, in Veneto, situated between the Piave and Livenza rivers at the foot of the mountain region known as the Prealpi.  It was formed from the joining of the communities of Serravalle and Ceneda in 1866 and named Vittorio in honour of Victor Emmanuel II.  The Veneto suffix was added in 1923 to commemorate the decisive battle.

Also on this day:

1946: The birth of actor Michele Placido

1979: The birth of Italian football great Andrea Pirlo

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Domenico di Pace Beccafumi – artist

Painter from Siena experimented with rich colour 

Beccafumi's Madonna with Child, St Jerome and the Infant
St John is notable for its almost luminous colours

Considered one of the last true representatives of the Sienese school of painting, Domenico di Pace Beccafumi died on this day in 1551 in Siena.

He is remembered for his direction of the paving of the Duomo - cathedral - of Siena between 1517 and 1544, when he made ingenious improvements to the technical processes employed for this task, which in the end took more than 150 years to complete.

Domenico was born in Montaperti near Siena in about 1486. His father, Giacomo di Pace, worked on the estate of Lorenzo Beccafumi, whose surname he eventually took.

Seeing his talent for drawing, Lorenzo had taken an interest in him and recommended that he learn painting from the Sienese artist, Mechero.

In 1509 Di Pace Beccafumi travelled to Rome for a short period, where he learnt from artists working on the Vatican.

Back in Siena, he painted religious pieces for churches and was only mildly influenced by the trends dominating the neighbouring Florentine school.

Domenico Beccafumi: a self-portrait

He designed scenes from the Old Testament to decorate the floor of the cathedral and also painted frescoes for Palazzo Pubblico in the city.

Di Pace Beccafumi is renowned for his use of rich, almost luminous colours. One of his paintings, which was rediscovered only in 1983, is Madonna with Child, St Jerome and the Infant St John. It shows Mary wearing a blue robe lined with an almost iridescent pale green. The painting is now in a collection in Madrid.

Siena had been an artistic rival of Florence, but wars and natural disasters had caused a decline by the 15th century. Stylistically, Beccafumi was the last in a long line of Sienese artists to use intense colour to express emotion and passion in his paintings.

The main altar of the Duomo di Siena
and Beccafumi's mosaic floor

Travel tip:

Siena’s Duomo, was designed and completed between 1215 and 1263 on the site of an earlier structure. It has a beautiful façade built in Tuscan Romanesque style using polychrome marble. Inside, its inlaid marble mosaic floor is one of the most ornate of its kind in Italy and covers the whole floor of the cathedral. The uncovered floor can be seen for only a few weeks each year, usually including September. The rest of the year it is kept covered, with only a few panels on display at a time. Half of the 13 Scenes from the life of Elijah in the transept of the cathedral were designed by Domenico Beccafumi, as well as Moses Striking Water on the Rock and Moses on Mount Sinai. His final contribution to the floor was The Sacrifice of Isaac, completed in 1547, which is in front of the main altar.

A monument to the Battle of Montaperti

Travel tip:

Montaperti, where Di Pace Beccafumi was born, is part of the comune (municipality) of Castelnuovo Berardenga in the province of Siena. Since 1932 it has been included in the Chianti wine production area. The famous Battle of Montaperti fought between Guelphs and Ghibellines took place there on September 4, 1260.

Also on this day:

1892: The birth of Metropolitan Opera star Ezio Pinza

1939: The birth of murdered anti-Mafia magistrate Giovanni Falcone

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Federico II Gonzaga – Duke of Mantua

Ruler received a valuable education at the papal court

Federico Gonzaga, aged about 10, painted
by Francesco Francia

Federico Gonzaga, who became the ruler of Mantua and Montferrat, was born on this day in 1500 in Mantua.

He spent his childhood living as a political hostage, first at the court of Pope Julius II in Rome and then at the court of Francis I of France.

It wasn’t perhaps an ideal start in life, but historians believe the political, social and cultural education he received in the company of popes, cardinals, and kings helped shape him as a future ruler.

Federico was the son of Francesco II Gonzaga and Isabella d’Este. His godfather was Cesare Borgia, Machiavelli’s model for the ideal Renaissance Prince.

His father, Francesco, was captured by the Venetians during battle and held hostage for several months. While he was absent, his wife, Isabella, ruled Mantua.

Francesco managed to secure his own release only by agreeing to send his son, Federico, to be a hostage at the papal court.

After the death of Pope Julius II in 1513, Federico was sent to the court of the new King of France, Francis I, where he became a favourite, as he had interests in common with the King.

Titian's 1525 portrait of Federico as an adult
can be seen at the Prado museum in Madrid

After the death of his father in 1519, Federico returned to rule Mantua and established Isabella Boschetti as his mistress there.

He was later created Duke of Mantua by the Emperor Charles V and did not intervene when the Imperial Troops passed through his territory in 1527 on their way to lay siege to Rome.

He married Margaret of Montferrat in 1531 and when the last male heir to Montferrat died, Federico became Marquess of Montferrat, a title his descendants held until the 18th century.

He commissioned Palazzo Te to be built as a summer palace just outside Mantua.

Federico had long suffered from syphilis and died of the disease in 1540.

His son, Francesco, briefly held the title of Duke of Mantua before dying while still a teenager. His second son, Guglielmo, became Duke of Mantua and Marquess of Montferrat and carried on the line.

The Palazzo Ducale was the seat of the Gonzaga family

Travel tip:

Mantua is an atmospheric old city in Lombardy, to the southeast of Milan, famous for its Renaissance Palazzo Ducale, the seat of the Gonzaga family between 1328 and 1707. The Camera degli Sposi is decorated with frescoes by Andrea Mantegna, depicting the life of Ludovico III Gonzaga and his family, who ruled Mantua for 34 years in the 15th century. The beautiful backgrounds of imaginary cities and ruins reflect Mantegna’s love of classical architecture.

The Palazzo Te was designed for Federico as a summer
residence just outside the walls of Mantua

Travel tip:

Palazzo Te, designed for Federico as a summer residence, is a fine example of the Mannerist school of architecture and is the masterpiece of the architect Giulio Romano. The name for the palace came about because the location chosen had been the site of the Gonzaga family stables at Isola del Te on the edge of the marshes just outside Mantua’s city walls. After the building was completed a team of plasterers, carvers and painters worked on the interior for ten years until all the rooms were decorated with beautiful frescoes.

Also on this day:

1510: The death of Renaissance artist Sandro Botticelli

1963: The birth of motorcycle world champion Luca Cadalora

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